Topical Pain Medication: Compounding Personalized Pain Management Options

Topical Pain Medication: Compounding Personalized Pain Management Options

Author: Bob Brensel | President, Pharmacist | ScriptWorks

Bob Brensel, RPh, earned his Pharmacy Degree at University of the Pacific in Stockton, California in 1980. He was honored as a student with the Longs Drugs Stores, “Outstanding Intern Scholarship” in 1977. Read More →

ScriptWorks, a PCAB-accredited compounding pharmacy serving California statewide, specializes in pain management compounding for patients with different types of pain.

In each clinical decision, practitioners must consider several factors to decide what may work best for their patients. Oftentimes, patients may not achieve optimal results with mass-produced, commercially available medications. Prescribers often reach out to the clinical pharmacists at ScriptWorks to develop compounded medication for providing patients more customized/targeted approaches as well as alternatives to addictive opioid-based pain medications

Topical Pain Medication

One therapy option might be topical pain medication that involves multiple drugs that may be used for acute musculoskeletal pain (strains and sprains) or chronic musculoskeletal pain.

Topical pain medications are applied externally and are absorbed through the skin.

They potentially exert their effects close to the sight of application and there should be little systemic uptake or distribution. Topical applications potentially limit systemic adverse side effects by minimizing systemic concentrations of the drug and avoiding the stomach and first pass metabolism in the liver. 

One of the keys to topical or transdermal compounding is to use a base that shows good skin penetration and can deliver the active ingredients to the target site. This typically involves a base with appropriate properties, such as optimal viscosity, compatibility with the active ingredient, and skin compatibility.

Uses of Topical Pain Medication (gels/creams)

Here are some examples of pain conditions for which we compound permeation enhanced topical gels or creams are prescribed.

  • Arthritis
  • Ankle Pain
  • Back Pain
  • Burning Foot Syndrome
  • Carpal Tunnel Syndrome
  • Diabetic Neuropathy
Woman with Arthritis in Need of Topical Pain Medication
  • Fibromyalgia
  • Gout
  • Knee Pain
  • Muscle Spasms
  • Neuropathic Pain
  • Plantar Fasciitis
  • Post Herpetic Neuralgia
  • Shingles
  • Shoulder Pain
  • Tennis Elbow
  • TMJ/TMD (Temporomandibular Disorders)

Topical Formulas from the East Bay’s Most Trusted Compounding Pharmacy

Some of the medications that can be considered in our topical formulas are:

  • NSAIDs
  • Muscle Relaxants
  • Neuropathic Drugs
  • Anesthetics
  • NMDA receptor blocker analgesics and calcium channel blockers
Topical Pain Medication Gels and Creams


ScriptWorks’ Topical Anesthetic

We make it easy for CA medical practitioners to prescribe pain medications for their patients. Simply fax in our easy to use form, with desired medications options selected.

Remember to always have your compounded  prescription filled at a PCAB-accredited compounding pharmacy. Get in touch with ScriptWorks today.

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